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KMID : 0360220130540010160
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Journal of the Korean Ophthalmological Society
2013 Volume.54 No. 1 p.160 ~ p.164
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A Case of IgG4-Related Sclerosing Disease Involving the Eyelid in an Idiopathic Sclerosing Myositis Patient
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Yoon Je-Hwan
Jung Jee-Woong
Chi Mi-Jung
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Abstract
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Purpose: To report a case of IgG4-related sclerosing disease involving the eyelid in an idiopathic sclerosing myositis patient.
Case summary: A 51-year-old woman presented with swelling, redness, and tenderness of the left lower eyelid of 1 month duration had taken an immunosuppressant for idiopathic sclerosing myositis. Eye movements showed limitation all directions but there was no exophthalmos. A palpable mass was noted in the left lower eyelid. The left extraocular muscles were hypertrophied but the lacrimal gland was normal on orbital magnetic resonance imaging. IgG4-related sclerosing disease was confirmed by immunostained biopsy from the left lower eyelid, showing infiltration of IgG4-positive lymphoplasmacytic cells. The patient was given oral steroids and an immunosuppressant and the symptoms did not recur for at least 7 months. Conclusions: IgG4-related sclerosing disease involving ocular adnexa usually consists of bilateral lacrimal gland involvement. Additionally, the orbital soft tissue involvement without dacryoadenitis is rare. The authors of the present study report a case of IgG4-related sclerosing disease involving the left lower eyelid in an idiopathic sclerosing myositis patient and should be considered in the differential diagnosis of eyelid masses.
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KEYWORD
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Eyelid, Idiopathic sclerosing myositis, IgG4-related sclerosing disease, Lacrimal gland
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